Autism or Autistic Spectrum Disorder is a graving problem of the present era. That has shown an alarming increase in the fast decade. The prevalence of this condition in the world is very high in India its incidence rate is calculated per year as 1 to 2 %. The factors like genetic problems autoimmune conditions and neurological abnormalities have been identified as the causes of autism for ASD. No definite reason is so far identified for the disorder in date.Autism involves atypical brain development which orphan becomes apparent in behaviour and social development before the child is 3 years old. It can be characterized by impairments in social interaction and communication as well as restricted interest and stereotyped behaviour characterization independent of underlying neurological defects. other characteristics include repetition like task-seen behaviour and scenery interests.Genetic factors may be the most significant cause of autism spectrum disorders. Autism prototype disorder for the pervasive developmental disorder is believed to be a complex genetic and neurological disorder that generally throughout a person’s life.

Low Weight may be due to various underlying causes like Malnutrition, Malabsorption Syndrom, Pthisis, Indigestion, Worm Infestation. Children are seen gaining weight which remains constant with the help of Ayurveda.

Down syndrome is a genetic disorder with abnormality in number of chromosomes where extra genetic material from chromosome 21 transferred to a newly formed embryo having 47 chromosomes in their cells instead of 46 normal number of chromosomes. Hence it is also known as trisomy 21.In every cell in the human body there is a nucleus, where genetic material is stored in genes. genes carry the codes responsible for all of our inherited traits and are grouped along rod like structures called chromosome. Typically, the nucleus of each cell contains 23 pairs of chromosomes, half of which are inherited from each parent. Down syndrome occurs when an individual has a full or partial extra copy of chromosome 21.This additional genetic material alters the course of development and causes the characteristics associated with down syndrome.The main cause, women who are 35 years or older when they become pregnant are more likely to have a pregnancy altered by down syndrome then women who become pregnant at younger age. However, the majority of babies with down syndrome are born to mothers less than 35 years old because there are many more births among young women.